Clinical Dermatology Review

ORIGINAL ARTICLE
Year
: 2018  |  Volume : 2  |  Issue : 2  |  Page : 58--63

A randomized, assessor-blinded, comparative study to evaluate the efficacy and safety of oat extract-based moisturizer in adult individuals with dry skin


Sarvajnamurthy Aradhya Sacchidanand1, Satish Udare2, Dhammraj Madhukar Borade3, Varsha Narayanan4, Sagar Katare5, Ashish Mane6, Agam Shah7 
1 Consultant Dermatologist, Sujala Polyclinic and Laboratory, Basaveshwaranagar, Bengaluru, Karnataka, India
2 Consultant Dermatologist, Sparkle Skin Aesthetic Centre, Vashi, Navi Mumbai, Maharashtra, India
3 Medical Advisor, Medical Affairs, Wockhardt Limited, Wockhardt Towers, Mumbai, Maharashtra, India
4 Head, Medical Affairs, Wockhardt Limited, Wockhardt Towers, Mumbai, Maharashtra, India
5 Medical Monitor, Clinical Operations, Wockhardt Limited, Wockhardt Towers, Mumbai, Maharashtra, India
6 Project Manager, Clinical Operations, Wockhardt Limited, Wockhardt Towers, Mumbai, Maharashtra, India
7 Head, Clinical Operations, Wockhardt Limited, Wockhardt Towers, Mumbai, Maharashtra, India

Correspondence Address:
Dhammraj Madhukar Borade
Medical Advisor, Medical Affairs, Wockhardt Limited, Wockhardt Towers, Bandra Kurla Complex, Mumbai - 400 051, Maharashtra
India

Background: Dry skin or xeroderma is a very frequent condition which occurs at any age. Moisturizers including conventional oatmeal have been widely used to improve dry skin conditions. Oat-based moisturizer can protect, hydrate, and promote the endogenous barrier repair. Aim: This study aims to evaluate the efficacy and safety of oat extract-based moisturizer in adult individuals with dry skin. Materials and Methods: This study was a treatment-randomized, assessor-blinded, no treatment controlled, comparative study. A total of 36 individuals were included in the study. Oat extract-based moisturizer (test product) and control treatment (no product application) were randomized, as per randomization plan and applied to all individuals on the surface of volar forearm 2 cm (1 cm radius) in diameter. In addition, right cheek as control site and left cheek as test site (oat extract-based moisturizer lotion) were considered for sebum level and facial skin pH analysis. Results: Oat extract-based moisturizer possessed excellent skin moisturizing properties. Both the Corneometer® and modified Kligman score, respectively, showed significant improvement (P < 0.0001) in skin hydration and decrease in skin dryness with respect to baseline till 24 h postapplication. Furthermore, Cutometer® reading had statistically significant increase in skin elasticity as compared to baseline till 6 h postapplication. There was no statistically significant effect on skin pH and sebum level as compared to control treatment. This concludes that oat extract-based moisturizer is effective in improving skin hydration and elasticity without any change in skin pH and sebum levels. Conclusion: Test product (oat extract-based moisturizer lotion) was safe and well tolerated. Efficacy analysis showed that the effect of oat extract-based moisturizer was significant in terms of skin hydration and skin elasticity.


How to cite this article:
Sacchidanand SA, Udare S, Borade DM, Narayanan V, Katare S, Mane A, Shah A. A randomized, assessor-blinded, comparative study to evaluate the efficacy and safety of oat extract-based moisturizer in adult individuals with dry skin.Clin Dermatol Rev 2018;2:58-63


How to cite this URL:
Sacchidanand SA, Udare S, Borade DM, Narayanan V, Katare S, Mane A, Shah A. A randomized, assessor-blinded, comparative study to evaluate the efficacy and safety of oat extract-based moisturizer in adult individuals with dry skin. Clin Dermatol Rev [serial online] 2018 [cited 2019 Jun 18 ];2:58-63
Available from: http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2018;volume=2;issue=2;spage=58;epage=63;aulast=Sacchidanand;type=0