• Users Online: 136
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2018  |  Volume : 2  |  Issue : 2  |  Page : 58-63

A randomized, assessor-blinded, comparative study to evaluate the efficacy and safety of oat extract-based moisturizer in adult individuals with dry skin


1 Consultant Dermatologist, Sujala Polyclinic and Laboratory, Basaveshwaranagar, Bengaluru, Karnataka, India
2 Consultant Dermatologist, Sparkle Skin Aesthetic Centre, Vashi, Navi Mumbai, Maharashtra, India
3 Medical Advisor, Medical Affairs, Wockhardt Limited, Wockhardt Towers, Mumbai, Maharashtra, India
4 Head, Medical Affairs, Wockhardt Limited, Wockhardt Towers, Mumbai, Maharashtra, India
5 Medical Monitor, Clinical Operations, Wockhardt Limited, Wockhardt Towers, Mumbai, Maharashtra, India
6 Project Manager, Clinical Operations, Wockhardt Limited, Wockhardt Towers, Mumbai, Maharashtra, India
7 Head, Clinical Operations, Wockhardt Limited, Wockhardt Towers, Mumbai, Maharashtra, India

Correspondence Address:
Dhammraj Madhukar Borade
Medical Advisor, Medical Affairs, Wockhardt Limited, Wockhardt Towers, Bandra Kurla Complex, Mumbai - 400 051, Maharashtra
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/CDR.CDR_37_17

Rights and Permissions

Background: Dry skin or xeroderma is a very frequent condition which occurs at any age. Moisturizers including conventional oatmeal have been widely used to improve dry skin conditions. Oat-based moisturizer can protect, hydrate, and promote the endogenous barrier repair. Aim: This study aims to evaluate the efficacy and safety of oat extract-based moisturizer in adult individuals with dry skin. Materials and Methods: This study was a treatment-randomized, assessor-blinded, no treatment controlled, comparative study. A total of 36 individuals were included in the study. Oat extract-based moisturizer (test product) and control treatment (no product application) were randomized, as per randomization plan and applied to all individuals on the surface of volar forearm 2 cm (1 cm radius) in diameter. In addition, right cheek as control site and left cheek as test site (oat extract-based moisturizer lotion) were considered for sebum level and facial skin pH analysis. Results: Oat extract-based moisturizer possessed excellent skin moisturizing properties. Both the Corneometer® and modified Kligman score, respectively, showed significant improvement (P < 0.0001) in skin hydration and decrease in skin dryness with respect to baseline till 24 h postapplication. Furthermore, Cutometer® reading had statistically significant increase in skin elasticity as compared to baseline till 6 h postapplication. There was no statistically significant effect on skin pH and sebum level as compared to control treatment. This concludes that oat extract-based moisturizer is effective in improving skin hydration and elasticity without any change in skin pH and sebum levels. Conclusion: Test product (oat extract-based moisturizer lotion) was safe and well tolerated. Efficacy analysis showed that the effect of oat extract-based moisturizer was significant in terms of skin hydration and skin elasticity.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed291    
    Printed23    
    Emailed0    
    PDF Downloaded58    
    Comments [Add]    

Recommend this journal